Pregledni rad
https://doi.org/10.69589/hsv.40.1.1
Bone marrow fat and physical activity in humans: a systematic review
Marija Rakovac
orcid.org/0000-0003-0098-4938
; University of Zagreb Faculty of Kinesiology
*
Bruno Lazinica
orcid.org/0000-0001-8788-7334
; University of Zagreb Faculty of Kinesiology
* Dopisni autor.
Sažetak
Bone marrow fat (BMF) is an adipose tissue depot negatively correlated with bone mineral density and
hematopoiesis. The influence of physical activity (PA) on BMF is still poorly understood. The aim of this study was to systematically analyze literature investigating the association between PA/exercise and BMF in humans. The literature search (MEDLINE, Scopus, SPORTDiscus, Web of Science) yielded 16 (9 cross-sectional/7 intervention) studies exploring: the relationship between practicing sports and BMF in athletes; PA and BMF in the general population; the effect of exercise during/reambulation after prolonged bed rest on BMF. Athletes practicing high-impact sports had a lower BMF than non-athletes in load-bearing skeletal regions (lumbar vertebra, mid-tibia, femoral neck). Active non-athletes had a lower BMF than inactive persons. High-volume weight-bearing activities were associated with a more significant BMF decrease. The adipogenic effect of estrogen deficiency on BMF was observed in oligoamenorrheic athletes. The impact of reambulation after prolonged bed rest is still inconclusive. Based on the results of the studies, high-impact PA is associated with lower BMF in load-bearing skeletal regions. There is a lack of randomized controlled trials and a standardized diagnostic methodology. Future studies should include different populations, larger samples, and longer interventions, and analyze different skeletal regions.
Ključne riječi
bone health, bed rest, exercise, marrow adipose tissue, sport
Hrčak ID:
333480
URI
Datum izdavanja:
23.6.2025.
Posjeta: 853 *