Ostalo
https://doi.org/10.20471/LO.2025.53.01.06
The neuroendocrine tumor of the ileocecal valve presented as an obstructive ileus – a case report and literature review
Marijan Tepeš
orcid.org/0000-0001-7283-4344
; Department of Clinical Medicine, Faculty of Dental Medicine and Health Osijek, Croatia and Department of Surgery, General Hospital Našice, Našice, Croatia
Zrinko Madžar
; Department of Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Dag Dušanić
; Department of Pathology, General Hospital Našice, Našice, Croatia
Vesna Čosić
; Department of Pediatrics and Gynecology with Obstetrics, Faculty of Dental Medicine and Health Osijek, Osijek, Croatia
Blaženka Mikšić
; Department of Clinical Medicine, Faculty of Dental Medicine and General Hospital Dr. Josip Benčević Slavonski Brod, Slavonski Brod, Croatia
Mario Puljiz
; Department of Gynecologic Oncology, Division of Surgery, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia and Faculty of Medicine, University J. J. Strossmayer, Osijek, Croatia
Denis Klapan
; Department of Surgery and Anesthesiology with Resuscitation, Faculty of Dental Medicine and Health Osijek, Osijek, Croatia
Andreja Bartulić
; Faculty of Medicine, University J. J. Strossmayer, Osijek, Croatia and Department of Gastroenterology, University Hospital Center Osijek, Osijek, Croatia
Josipa Flam
; Faculty of Medicine, University J. J. Strossmayer, Osijek, Croatia and Department of Oncology, University Hospital Center Osijek, Osijek, Croatia
Tomislav Madžar
; University of Applied Health Sciences, Zagreb, Croatia
Tomislav Jurić
; Faculty of Medicine, University J. J. Strossmayer, Osijek, Croatia
Romana Marušić
; Faculty of Medicine, University J. J. Strossmayer, Osijek, Croatia and National Memorial Hospital Dr Juraj Njavro, Vukovar, Croatia
Hrvoje Centner
; Faculty of Medicine, University J. J. Strossmayer, Osijek, Croatia
Sažetak
Neuroendocrine tumors of the ileocecal valve are rare, frequently manifesting with nonspecific symptoms that complicate early diagnosis. This report examines a 66-year-old woman with significant comorbidities, including diabetes mellitus and chronic renal failure, who presented to the emergency department with severe cramping abdominal pain, vomiting, and a mild fever. Initial imaging and laboratory tests yielded inconclusive results. However, a CT scan of the abdomen and pelvis revealed a small bowel obstruction at the ileocecal valve, caused by a tumor mass. Given the acute nature of her symptoms, the patient underwent an emergency right hemicolectomy with ileocolostomy. Histopathological analysis confirmed a 4 cm, well-differentiated grade 2 neuroendocrine tumor with lymphovascular invasion, along with metastases in 4 out of 17 examined lymph nodes. The patient had an uncomplicated postoperative course and was discharged on the tenth day in stable condition. This case highlights the need to consider neuroendocrine tumors in the differential diagnosis of bowel obstruction when imaging reveals a mass near the ileocecal region. Early detection and prompt surgical intervention are essential for optimal outcomes. Due to the rarity of neuroendocrine tumors in this anatomical location, this case provides valuable insights into the diagnostic anmanagement complexities they pose. Continuous follow-up with a multidisciplinary team remains essential to monitor for potential recurrence or metastasis.
Ključne riječi
neuroendocrine tumor; obstructive ileus; chromogranin A; proton pump inhibitors; false positive
Hrčak ID:
334412
URI
Datum izdavanja:
21.8.2025.
Posjeta: 941 *