Sažetak sa skupa
Retrograde cricopharyngeal dysfunction – a case report and literature review
Ana Đanić Hadžibegić
orcid.org/0000-0001-8513-5032
; KBC Zagreb, Kišpatićeva 12, 10000 Zagreb, Hrvatska
Agata Ladić
; KB Dubrava, Avenija Gojka Šuška 6, 10000 Zagreb, Hrvatska
Sažetak
Retrograde cricopharyngeal dysfunction (R-CPD) is a recently recognized clinical entity characterized by the
inability to belch, leading to a constellation of distressing symptoms such as socially disruptive gurgling
sounds, abdominal bloating, chest pressure, and excessive flatulence. This literature review aims to synthesize
current knowledge regarding the pathophysiology, clinical presentation, diagnostic challenges, and
management of R-CPD. The exact etiology remains unclear, but failure of transient relaxation of the
cricopharyngeus muscle in response to gastric gas appears central to the disorder. Unlike classic dysphagia,
patients with R-CPD typically have no difficulty swallowing solids or liquids, which often delays diagnosis.
Diagnostic work-up may include high-resolution manometry, video fluoroscopic swallowing studies, and
endoscopic evaluation, although diagnosis remains largely clinical. Botulinum toxin injection into the
cricopharyngeus muscle has emerged as the most effective treatment, with high success rates and lasting relief
for most patients. Repeated injections or cricopharyngeal myotomy may be considered for those with recurrent
symptoms. In addition to the literature review, this presentation includes a case report of a patient diagnosed
with R-CPD, illustrating the typical symptom progression, diagnostic process, and therapeutic outcome
following botulinum toxin treatment. This review highlights the importance of recognizing R-CPD as a distinct
clinical syndrome and emphasizes the need for interdisciplinary collaboration in diagnosis and management.
Increased awareness among gastroenterologists, otolaryngologists, and speech-language pathologists is
essential for timely intervention and improved patient outcomes.
Ključne riječi
abelchia; botulinum toxin; cricopharyngeal myotomy; retrograde cricopharyngeal dysfunction
Hrčak ID:
336293
URI
Datum izdavanja:
10.11.2025.
Posjeta: 194 *