Pregledni rad
https://doi.org/10.18054/pb.v127i1-2.35816
Perioperative impact of high-flow nasal oxygenation in obstetric general anesthesia
Ana Vuzdar Trajkovski
orcid.org/0009-0001-8487-1182
; University Department for Anesthesiology, Resuscitation, Intensive Care and Pain Therapy, Zagreb University Hospital Center, Zagreb, Croatia
*
Vesna Grgić
; University Department for Anesthesiology, Resuscitation, Intensive Care and Pain Therapy, Zagreb University Hospital Center, Zagreb, Croatia
Marina Katalinić Novak
; University Department for Anesthesiology, Resuscitation, Intensive Care and Pain Therapy, Zagreb University Hospital Center, Zagreb, Croatia
Krešimir Reiner
; University Department for Anesthesiology, Resuscitation, Intensive Care and Pain Therapy, Zagreb University Hospital Center, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia
Ivan Šklebar
orcid.org/0000-0002-4557-7626
; University Department for Anesthesiology, Resuscitation, Intensive Care and Pain Therapy, Zagreb University Hospital Center, Zagreb, Croatia; School of Medicine, Catholic University of Croatia, Zagreb, Croatia; Bjelovar University of Applied Sciences, Bjelovar, Croatia
* Dopisni autor.
Sažetak
Background and purpose: High-flow nasal oxygenation (HFNO) is gaining attention in anesthesia for cesarean sections under general anesthesia due to its potential to reduce hypoxemia - a major cause of maternal morbidity and mortality. Pregnant patients face increased risk from anatomical and physiological changes, including airway edema, reduced functional residual capacity, and increased aspiration risk. Traditional preoxygenation with 100% oxygen via a face mask may not provide adequate oxygen reserves, prompting exploration of HFNO as an alternative. This paper reviews current evidence on the use of HFNO preoxygenation during anesthesia induction for cesarean sections.
Materials and methods: An extensive literature search was performed to evaluate existing research on HFNO as a preoxygenation technique in obstetric general anesthesia.
Results: Eight studies were identified that assess HFNO in this context. While some report inferior performance in achieving optimal end-tidal oxygen fraction compared to face mask methods, others highlight benefits. A 2021 randomized trial found HFNO yielded higher arterial oxygen tension and end tidal oxygen fraction post-intubation. Additionally, a recent multicenter pilot study reported no desaturation events among pregnant patients, supporting HFNO’s safety and potential efficacy.
Conclusion: HFNO offers advantages such as prolonged safe apnea time and ease of application. However, its effectiveness in the obstetric population remains insufficiently validated. More robust clinical trials are required before HFNO can be integrated into standard anesthetic protocols for cesarean sections.
Ključne riječi
cesarean section; airway management; oxygen therapy; obstetrics
Hrčak ID:
340262
URI
Datum izdavanja:
1.12.2025.
Posjeta: 0 *