Pregledni rad
https://doi.org/10.26332/1xsrvv94
Diagnostics and Treatment of Malignant Ovarian Tumors
Ivana Maurac Pašalić
; Department of Obstetrics and Gynaecology, University Hospital Centre Zagreb, Croatia, School of Medicine, University of Zagreb, Croatia
Sara Šota
; School of Medicine, University of Zagreb, Croatia
Miriam Šoletić
; School of Medicine, University of Zagreb, Croatia
Mato Pavić
; Department of Obstetrics and Gynaecology, University Hospital Centre Zagreb, Croatia, School of Medicine, University of Zagreb, Croatia
Sažetak
Malignant ovarian tumors represent a heterogeneous group of neoplasms and a significant clinical challenge. Due to non-specific symptoms in the early stages, they are often diagnosed late, resulting in poor prognosis. Diagnostic evaluation involves a combination of medical history, physical examination, tumor marker assessment, and imaging techniques. Transvaginal ultrasound is the first-line imaging modality, followed by CT, MRI, or PET/CT as needed. Accurate staging is essential for choosing the optimal therapeutic approach. Standard treatment consists of surgery and platinum-based chemotherapy, with PARP inhibitors and anti-angiogenic therapies used in maintenance. In selected young patients, fertility-sparing surgery may be considered. The management of recurrent disease is individualized based on patient characteristics, tumor biology and previous response to therapy.
Ključne riječi
Ovarian Neoplasms; Chemotherapy; Adjuvant; Ultrasonography; Fertility Preservation, Recurrence
Hrčak ID:
342748
URI
Datum izdavanja:
29.12.2025.
Posjeta: 243 *