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https://doi.org/10.20471/acc.2025.64.03.18

Hematology Patients are at a Higher Risk of Late Complications of Totally Implantable Venous Access Ports – A Single Center Retrospective Cohort Study

Bruno Lovreković ; Division of general and sport traumatology and orthopoedics, Department of surgery, Merkur University Hospital Zagreb, Croatia
Delfa Radić Krišto ; Division of hematology, Department of internal medicine, Merkur University Hospital, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia
Njetočka Gredelj Šimec ; Division of hematology, Department of internal medicine, Merkur University Hospital, Zagreb, Croatia
Helena Jerkić orcid.org/0000-0002-1650-4735 ; Department of Cardiology, Sestre milosrdnice University Hospital Centre Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia *

* Dopisni autor.

Sažetak

Totally implantable venous access ports (TIVAPs) are central venous devices for
long-term intravenous treatment, most commonly used in oncology patients. Despite many benefits,
their usage can be associated with severe complications. The purpose of this study was to determine early
and late complications of TIVAPs insertion.
Methods: We performed a single-center retrospective study in University Hospital Merkur and enrolled
90 hematology and 7 oncology patients who had TIVAPs inserted in the period between November
2013 and May 2018. The procedure of insertion was performed by a cardiologist under fluoroscopy
through the right subclavian vein in local anesthesia. Our main focus was on early and late complications
of TIVAPs insertion. Early complications occurred in the first 30 days of insertion and late complications
beyond 30 days after insertion.
Results: Complications of TIVAPs insertion occurred in 26 patients (26.8 %); all of them were
hematology patients. Early complications were found in 8 (8.2%) patients and late complications in
18 (18.5%) patients. Pneumothorax as an early complication was found in 2 (2.1%) patients. Early infections
were found in 5 (5.1%) patients and all were classified as bloodstream infections. One (1.03%)
patient exhibited wound healing problems and required TIVAP extraction. Late complications were
found in 18 (18.5%) patients: one (1.03%) port pocket infection, 16 (16.5%) bloodstream infections and
one (1.03%) late catheter related venous thrombosis (1.03%).
Conclusion: The implantation and use of TIVAPs is a valuable method in the treatment of oncology
and hematology patients. However, in view of the number of TIVAPs complications observed in our study,
we can conclude that hematology patients are at a higher risk for developing TIVAPs-related late infections.

Ključne riječi

totally implantable venous access port; complication of insertion; hematology patients

Hrčak ID:

342944

URI

https://hrcak.srce.hr/342944

Datum izdavanja:

30.9.2025.

Podaci na drugim jezicima: hrvatski

Posjeta: 384 *