Acta clinica Croatica, Vol. 64. No. 4, 2025.
Izvorni znanstveni članak
https://doi.org/10.20471/acc.2025.64.04.12
Labor Induction by Prostaglandins: Comparison of the Efficacy of Misoprostol and Dinoprostone
Matija Šego
; School of Medicine, University of Zagreb, Zagreb, Croatia
Mirna Došen
; School of Medicine, University of Zagreb, Zagreb, Croatia
Petra Glad Štritof
; Department of Obstetrics and Gynecology, Sveti Duh University Hospital, Zagreb, Croatia
Paulo Zekan
; Department of Obstetrics and Gynecology, Sveti Duh University Hospital, Zagreb, Croatia
Marija Gotić Pavasović
; Department of Obstetrics and Gynecology, Sveti Duh University Hospital, Zagreb, Croatia
Vladimir Blagaić
; Department of Obstetrics and Gynecology, Sveti Duh University Hospital, Zagreb, Croatia
*
Alenka Boban Blagaić
; School of Medicine, University of Zagreb, Zagreb, Croatia
* Dopisni autor.
Sažetak
In developed countries, almost every fourth woman in labor is induced with the aim
of stimulating uterine contractions before the spontaneous onset of labor. The aim of this retrospective
study carried out at the Department of Gynecology and Obstetrics, Sveti Duh University Hospital was
to compare the efficacy of using two prostaglandin preparations, misoprostol and dinoprostone, in labor
induction. A total of 200 female subjects were divided into 2 groups, a group induced by misoprostol
(N=100) and a group induced by dinoprostone (N=100). The criteria for inclusion in the study were
women with a live fetus admitted for programmed or indicated induction. The exclusion criteria were
the post-cesarean section condition and the fetus in a breech position. The results of the study showed
that the use of misoprostol significantly shortened the duration of labor and reduced the risk of cesarean
delivery compared to dinoprostone. Finally, the research showed the advantage of using misoprostol in
the induction of labor compared to the use of dinoprostone, which along with its stability at room temperature,
affordability and wide availability make it a good and safe agent for labor induction.
Ključne riječi
Labor induction; Misoprostol; Dinoprostone; Duration of labor; Cesarean section
Hrčak ID:
344726
URI
Datum izdavanja:
31.12.2025.
Posjeta: 273 *