Original scientific paper
https://doi.org/10.15644/asc60/1/5
Adjunctive Povidone-Iodine Improves Bleeding Outcomes in Step 2 of Periodontal Therapy: A Retrospective Cohort Study
Valentin Bartha
; Heidelberg University, Department for Conservative Dentistry, Germany
*
Boris Krumm
; Private practice, Frankfurt, Germany
Judith Schamuhn
; Private practice, Cologne, Germany
Aleksandra Kopunic
; Heidelberg University, Department for Conservative Dentistry, Germany
Marco M. Herz
; University of Tuebingen, Department for Conservative Dentistry, Germany
* Corresponding author.
Abstract
Background: This retrospective cohort study evaluated the effects of adjunctive povidone-iodine (PVP-I), full-mouth disinfection (FMD), and conventional full-mouth scaling (FMS) following Step 2
of periodontal therapy on clinical outcomes. Methods: Patient records from the Department of Conservative Dentistry, University Hospital Tuebingen (2004–2016), with complete periodontal data before (T0) and after Step 2 of periodontal therapy (T1), were analyzed. The influence of treatment modality, baseline bleeding on probing (BOP%), proportion of sites with probing pocket depth (PPD) ≥ 5 mm, age, smoking, diabetes, and re-evaluation interval on changes in BOP and PPD, as well as on the clinical endpoints BOP ≤ 20% and ≤ 4 sites with PPD ≥ 5 mm, was assessed using multivariable regression. Results: A total of 227 patients were included (52% female; mean ± SD age: 56.5 ± 11.2 years): 96 FMS, 93 FMD, and 38 PVP-I. Adjunctive PVP-I led to a significantly greater reduction in BOP compared with both FMD and FMS and substantially increased the likelihood of achieving BOP ≤ 20%
(adjusted OR = 11.5; p = 0.03), independent of baseline inflammation and re-evaluation period. For the pocket-related endpoint (≤ 4 sites with PPD ≥ 5 mm), regression models were unstable due to the small number of successful cases; baseline PPD % remained the only consistent predictor. Conclusion: Adjunctive PVP-I use was significantly associated with improved bleeding-related outcomes after Step 2 of periodontal therapy, whereas no additional benefit was observed for deep-pocket reduction. PVP-I may therefore enhance the resolution of gingival inflammation but does not substantially affect pocket closure beyond conventional mechanical therapy.
Keywords
Periodontitis; Periodontal Debridement; PovidoneIodine; Anti-Infective Agents; adjuvants, pharmaceutic; povidone-iodine; chlorhexidine;
Hrčak ID:
345314
URI
Publication date:
13.3.2026.
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