Acta clinica Croatica, Vol. 65. No. 1, 2026.
Pregledni rad
https://doi.org/10.20471/acc.2026.65.01.16
Psoriasis and Periodontitis – Shared Inflammatory Mechanisms and Clinical Implications
Katarina Dragun
; Department of Dermatology and Venereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
*
Filip Bosnić
; Department of Dermatology and Venereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Mislav Mokos
; Department of Dermatology and Venereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Karla Štajcar Čular
; Damira Dental Studios Ltd, Bishops Stortford, Hertfordshire, United Kingdom
Darko Božić
; School of Dental Medicine, University of Zagreb, Zagreb, Croatia
Mirna Šitum
; Department of Dermatology and Venereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; School of Dental Medicine, University of Zagreb, Zagreb, Croatia; Croatian Academy of Sciences and Arts, Zagreb, Croatia
* Dopisni autor.
Sažetak
Psoriasis is a chronic, autoimmune, genetically determined and frequently re-
curring skin disease characterized by specific clinical features in the form of er-
ythematous squamous plaques. The development of psoriasis is influenced by
genetic and environmental factors, as well as a complex inflammatory cascade.
To this day, there is no precise information identifying the main trigger of the in-
flammation and formation of psoriatic plaques. In patients suffering from psori-
asis, an increased prevalence of periodontitis has been observed. Severe forms
3
4
of periodontitis are the 6th most common chronic disease, with a prevalence
of 11.2% and affecting more than 800 million people worldwide. The chronic
inflammation and immune mechanisms involved in the development of this dis-
ease remain a subject of ongoing research and the search for key therapeutic
options. In this review paper, we explored the relationship between the chronic
inflammatory immune processes underlying psoriasis and periodontitis, as well
as the potential frequency and possibility of triggering the onset of a multisys-
tem disease, such as psoriasis, in patients with periodontal disease.
Ključne riječi
Psoriasis; Periodontitis; Systemic inflammation; Chronic infections
Hrčak ID:
345843
URI
Datum izdavanja:
27.3.2026.
Posjeta: 110 *