Acta clinica Croatica, Vol. 65. No. 2, 2026.
Original scientific paper
https://doi.org/10.20471/acc.2026.65.02.05
The Influence of Individual Factors on Adherence to Treatment in Patients With Peripheral Arterial Disease
Zoran Damnjanović
orcid.org/0000-0001-9780-6745
; School of Medicine, University of Niš, Niš, Serbia; Vascular Surgery Clinic, University Clinical Center Niš, Niš, Serbia
*
Nemanja Stepanović
; School of Medicine, University of Niš, Niš, Serbia; Vascular Surgery Clinic, University Clinical Center Niš, Niš, Serbia
Ivana Damnjanović
; School of Medicine, University of Niš, Niš, Serbia
Slobodan Tanasković
; School of Medicine, Belgrade University, Belgrade, Serbia; Vascular Surgery Clinic, “Dedinje” Cardiovascular Institute, Belgrade, Serbia
Nikola Ilić
; School of Medicine, Belgrade University, Belgrade, Serbia; Clinic for Vascular and Endovascular Surgery, University Clinical Centre of Serbia, Belgrade, Serbia
Predrag Gajin
; School of Medicine, Belgrade University, Belgrade, Serbia; Vascular Surgery Clinic, “Dedinje” Cardiovascular Institute, Belgrade, Serbia
Miloš Sladojević
; School of Medicine, Belgrade University, Belgrade, Serbia; Clinic for Vascular and Endovascular Surgery, University Clinical Centre of Serbia, Belgrade, Serbia
* Corresponding author.
Abstract
The aim of this study was to examine the influence of individual factors on adherence
to treatment in patients with peripheral arterial disease (PAD). The
study included 82 patients diagnosed with PAD (Fontaine IIa, IIb) and treated at
the Clinic for Vascular Surgery of the University Clinical Center Niš, during the
period from January 1, 2020 to December 31, 2020.
We found a significant correlation between the degree of adherence to treatment
and health-related quality of life in patients with PAD. Patients with a medium
and high degree of adherence had a significantly higher quality of life
compared to the respondents with a low degree of adherence.
The chi-square test of independence showed a significant correlation between
obesity (P = 0.007) and the number of medications in therapy (P < 0.001)
with adherence to therapy in patients with PAD.
Adherence was statistically significantly influenced by obesity and the number
of medications in therapy, while sex, age, smoking, diabetes, dyslipidemia,
the number of risk factors, and type of therapeutic modality did not show this
association.
Keywords
Individual factors; Adherence; Peripheral arterial disease
Hrčak ID:
347690
URI
Publication date:
10.6.2026.
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