Skoči na glavni sadržaj

Kratko priopćenje

https://doi.org/10.2478/10004-1254-60-2009-1893

Skin Decontamination with Mineral Cationic Carrier Against Sarin Determined In vivo

Ante Vučemilović ; Institute of Researches and Development of Defense Systems, Zagreb, Croatia
Mirko Hadžija ; Ruđer Bošković Institute, Zagreb, Croatia
Ivan Jukić ; Institute of Researches and Development of Defense Systems, Zagreb, Croatia


Puni tekst: engleski pdf 97 Kb

str. 173-177

preuzimanja: 994

citiraj


Sažetak

Our Institute’s nuclear, biological, and chemical defense research team continuously investigates and develops preparations for skin decontamination against nerve agents. In this in vivo study, we evaluated skin decontamination efficacy against sarin by a synthetic preparation called Mineral Cationic Carrier (MCC®) with known ion exchange, absorption efficacy and bioactive potential. Mice were treated with increasing doses of sarin applied on their skin, and MCC® was administered immediately after contamination. The results showed that decontamination with MCC® could achieve therapeutic efficacy corresponding to 3 x LD50 of percutaneous sarin and call for further research.

Ključne riječi

bioactive potential; MCC®; nerve agent; NOD mice; sorption powder; toxicity

Hrčak ID:

38395

URI

https://hrcak.srce.hr/38395

Datum izdavanja:

12.6.2009.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.302 *