Stručni rad
Dietary exposure assessment of ß-lactam antibiotic residues in milk on Croatian market
Natalija Vragović
; Center for Food Control, Medvedgradska 49, 10000 Zagreb, Croatia
D. Bažulić
; Residues Analysis Center, Medvedgradska 49, 10000 Zagreb, Croatia
N. Zdolec
; University of Zagreb, Faculty of Veterinary Medicine, Department of Food Hygiene and Technology, Heinzelova 55, 10000 Zagreb, Croatia
Sažetak
This paper presents the preliminary screening report of the occurrence of β-lactam antibiotic residues in milk on Croatian market. The intensive animal production sometimes leads to the unavoidable presence of residues of veterinary drugs in food. However, it is possible to reduce the presence of residues in foods of animal origin by using the principles of good veterinary and good manufacturing practices, continuous control of food and using risk assessment approach. Method used for determination of these antibiotics were validated according to the guidelines laid down by European Commission Decision 2002/657/EC. The estimated dietary exposure based on the data on average consumption of milk and the estimated concentration of amoxicillin, ampicillin, benzylpenicillin, cloxacillin, cephapirin, cefazolin, cefoperazone and ceftiofur does not exceed relevant toxicological reference value (acceptable daily intake). These indicate that milk on Croatian market contain very low levels of β-lactam antibiotic residues and toxsicological risk with regard to consuming of milk could not be considered as a public health problem.
Ključne riječi
dietary exposure; β-lactam antibiotics; milk; food safety
Hrčak ID:
84727
URI
Datum izdavanja:
19.7.2012.
Posjeta: 2.004 *