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Hrvatski časopis za prehrambenu tehnologiju, biotehnologiju i nutricionizam, Vol. 9 No. 1-2, 2014.

Pregledni rad

Tetracycline antibiotics and determination of their residues in food

Sanja Makovec ; Prehrambeno-biotehnološki fakultet Sveučilišta u Zagrebu, Pierottijeva 6, Zagreb
Blaženka Kos ; Laboratorij za tehnologiju antibiotika, enzima, probiotika i starter kultura, Zavod za biokemijsko inženjerstvo, Prehrambeno-biotehnološki fakultet Sveučilišta u Zagrebu, Pierottijeva 6, Zagreb
Jagoda Šušković ; Laboratorij za tehnologiju antibiotika, enzima, probiotika i starter kultura, Zavod za biokemijsko inženjerstvo, Prehrambeno-biotehnološki fakultet Sveučilišta u Zagrebu, Pierottijeva 6, Zagreb
Nina Bilandžić orcid id orcid.org/0000-0002-0009-5367 ; Laboratorij za određivanje rezidua, Odjel za veterinarsko javno zdravstvo, Hrvatski veterinarski institut, Savska 143, Zagreb

Puni tekst: hrvatski pdf 424 Kb

str. 7-16

preuzimanja: 4.454

citiraj

Sažetak

At the global level, almost 50% of the produced antibiotics are used in the prevention and therapies of domestic animals intended for human
consumption, and among them, tetracyclines are significant. Due to the broad spectrum of activity against Gram-positive and Gram-negative bacteria, rickettsia and viruses, relatively low toxicity, good tolerability and applications in various pharmaceutical forms, tetracycline antibiotics are widely used in human and veterinary medicine. Tetracyclines are products of secondary metabolism of bacteria of the genus Streptomyces, and are in use also as semisynthetic tetracyclines. Determination of antibiotic residues, including tetracyclines, in samples of animal origin, has become necessary in order to protect consumers and prevent the spread of antibiotic resistance. Control of antibiotic residues and maximum residue limits (MRLs) of antibiotics in certain organs, milk and tissues of animal origin are regulated at EU level. In order to control
tetracycline residues in food screening methods are used, such as various microbiological tests and ELISA methods. In case of positive results to tetracycline residues, above the prescribed maximum levels, confirmatory methods is applied, usually liquid chromatography with tandem mass spectrometry (LC-MS/MS).

Ključne riječi

antibiotics; tetracyclines; antibiotic resistance; food of animal origin; food control

Hrčak ID:

126090

URI

https://hrcak.srce.hr/126090

Datum izdavanja:

31.7.2014.

Podaci na drugim jezicima: hrvatski

Posjeta: 5.904 *