Pregledni rad

https://doi.org/10.15255/KUI.2014.020

1,3-Dipolar Cycloaddition (Part I): Synthesis of 1,2,3-Triazole Derivatives in Nucleoside Chemistry

D. Saftić ; Zavod za organsku kemiju i biokemiju, Institut Ruđer Bošković, Bijenička cesta 54, 10 000 Zagreb, Hrvatska
L. Krstulović ; Zavod za kemiju i biokemiju, Veterinarski fakultet, Sveučilište u Zagrebu Heinzelova 55, 10 000 Zagreb, Hrvatska
M. Bajić ; Zavod za kemiju i biokemiju, Veterinarski fakultet, Sveučilište u Zagrebu Heinzelova 55, 10 000 Zagreb, Hrvatska
B. Žinić ; Zavod za organsku kemiju i biokemiju, Institut Ruđer Bošković, Bijenička cesta 54, 10 000 Zagreb, Hrvatska

Sažetak

Copper catalysed Huisgen 1,3-dipolar cycloaddition of azides and alkynes which leads to 1,4-disubstituted-1,2,3-triazoles is a frequently used method in synthetic organic chemistry. Due to the simple reaction conditions, it has occupied an important place in the field of nucleoside chemistry since it enables preparation of a large number of potentially biologically active compounds with a number of interesting additional properties induced by the presence of 1,2,3-triazole structural motif in the molecule.

Ključne riječi

Click chemistry; nucleosides; 1,2,3-triazole nucleoside analogs

Hrčak ID:

145123

URI

https://hrcak.srce.hr/145123

Datum izdavanja:

17.9.2015.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.409 *