Izvorni znanstveni članak
https://doi.org/10.17508/CJFST.2018.10.1.03
Antioxidant activities and inhibitory effect of Taraxacum officinale, Cichorium intybus and Lectuca sativa on prooxidant induced lipid peroxidation in mice liver
SADAF ISHFAQ
; Department of Chemistry, University of Poonch, Rawalakot, Azad Kashmir, Pakistan
SYED MUBASHAR SABIR
orcid.org/0000-0002-3339-366X
; Department of Chemistry, University of Poonch, Rawalakot, Azad Kashmir, Pakistan
HAMADIA KHURSHID
; Department of Chemistry, University of Poonch, Rawalakot, Azad Kashmir, Pakistan
TAHIR ZAMAN
; Department of Chemistry, University of Poonch, Rawalakot, Azad Kashmir, Pakistan
ZULFIQAR AHMAD
; University College of Agriculture and Environmental Sciences, The Islamia University Bahawalpur, Pakistan
Sažetak
This study reports the antioxidant and protective properties of three dietary
plants, Taraxacum officinale, Cichorium intybus and Lectuca sativa on lipid
peroxidation in mice liver. Extracts showed significant (p = 0.0392) inhibition
against thiobarbituric acid reactive species (TBARS) induced using the pro-
oxidants iron (10 μM FeSO4) and sodium nitroprusside (5 μM) in liver
homogenates of mice. Free radical scavenging activity was evaluated by the
quenching of DPPH radical (p=0.00236). Extracts also showed metal chelating
activities (p=0.00143) and high antioxidant activity in phosphomolybdenum
assay (p=0.00246). The high content (p=0.000243) of phenolics and
flavonoids were detected in aqueous extracts of the plants which may be
responsible for antioxidant activities. Taraxacum officinale comparatively
showed higher antioxidant activities followed by Cichorium intybus and
Lectuca sativa. It is concluded that polyphenolic-rich extracts of studied plants
are potential sources of natural antioxidants.
Ključne riječi
antioxidant activity; iron chelation; medicinal plants; oxidative stress; phenolics
Hrčak ID:
200541
URI
Datum izdavanja:
25.5.2018.
Posjeta: 1.110 *