Pregledni rad

https://doi.org/10.15255/KUI.2019.035

Application of Mathematical Modelling in Development of Enzymatic Cascade Reactions

Nevena Milčić orcid.org/0000-0003-0712-2417 ; Fakultet kemijskog inženjerstva i tehnologije, Sveučilište u Zagrebu, Marulićev trg 19, 10 000 Zagreb
Morana Česnik ; Fakultet kemijskog inženjerstva i tehnologije, Sveučilište u Zagrebu, Marulićev trg 19, 10 000 Zagreb
Martina Sudar orcid.org/0000-0002-6734-1024 ; Fakultet kemijskog inženjerstva i tehnologije, Sveučilište u Zagrebu, Marulićev trg 19, 10 000 Zagreb
Zvjezdana Findrik Blažević orcid.org/0000-0002-5312-8951 ; Fakultet kemijskog inženjerstva i tehnologije, Sveučilište u Zagrebu, Marulićev trg 19, 10 000 Zagreb

Sažetak

Today, systems biocatalysis, i.e., the implementation of cascade reactions that mimic cellular metabolic pathways, is increasingly being used. Cascade reactions have numerous advantages over traditional chemical processes; however, in order to successfully optimize and transfer such complex systems to a larger, industrial scale, it is necessary to apply reaction engineering. This review paper provides examples of the successful application of mathematical modelling in development of enzymatic cascade reactions that demonstrate the importance and potential of this methodology.


This work is licensed under a Creative Commons Attribution 4.0 International License.

Ključne riječi

reaction engineering; biocatalysis; modelling; optimization; multi-enzymatic systems

Hrčak ID:

225290

URI

https://hrcak.srce.hr/225290

Datum izdavanja:

7.10.2019.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.528 *