Izvorni znanstveni članak
https://doi.org/10.20471/acc.2021.60.s1.16
Probiotics and High Fiber-Rich Diets Have Anti-Inflammatory Properties and Decline Chronic Kidney Disease Progression
Ingrid Prkačin
orcid.org/0000-0002-5830-7131
; Department of Internal Medicine, University Hospital Merkur, Zagreb, Croatia; Medical School, University of Zagreb, Zagreb, Croatia
Pavao Findri
; Medical School, University of Zagreb, Zagreb, Croatia
Ana Marija Novak
; Medical School, University of Zagreb, Zagreb, Croatia
Jakov Pleše
; Medical School, University of Zagreb, Zagreb, Croatia
Tomislav Bulum
; Clinic for Diabetes, Endocrinology and Metabolic Diseases Vuk Vrhovac, University Hospital Merkur, Zagreb, Croatia
Ivan Bubić
; Department of Internal Medicine, Faculty of Medicine University of Rijeka, Dept. of Clinical Sciences I, Faculty of Health Sciences University of Rijeka, Dept. of Nephrology, Dialysis and Kidney Transplantation, University Hospital Centre Rijeka
Sažetak
A well balanced, time-restricted diet with 50% more vegetables and restriction of
red meat can delay the progression of kidney damage. This paper suggests that such diet changes can
also have an immunoregulatory role, with adding pre/probiotics. There were two groups of patients
(20M/28F; age 67±9 years, estimated glomerular filtration rate 42,1±12 ml/min/1.73m2): group A
practiced a modified diet that consisted of certain nutritional changes (50% more vegetable intake,
reduction of red meat to twice per week), time-restricted eating (8 hours), and taking probiotics.
Group B was also taking probiotics; however, their nutrition included no restrictions on red meat intake,
they ate fewer vegetables, and there was no time-restricted eating.
After 3 months, therapy from Group A − a balanced, time-restricted diet plus probiotics, resulted
in weight loss (from 113±13 to 110±18 kg), body mass index decrease (from 36.4±5.1 to 34±5 kg/m2),
decrease in waist circumference (from 119±11 to 115±10 cm), as well as lower hsC-reactive protein by
8% (group A) and 5% (group B). The values of kidney function measurements after 3 months were
45,3±11 ml/min/1.73m² in group A, while in group B, those were 42,4±10 ml/min/1.73m² (p<0.05).
This study shows a positive correlation between the daily consumption of probiotics and decreased
progression of chronic kidney disease.
Ključne riječi
Probiotics; Fiber-rich diets; Chronic kidney disease
Hrčak ID:
260411
URI
Datum izdavanja:
1.1.2021.
Posjeta: 1.561 *