Skoči na glavni sadržaj

Pregledni rad

https://doi.org/10.20471/acc.2021.60.04.21

Modern Approach to Dyspepsia

Barbara Medić ; Zagreb Health Center-Center, Zagreb, Croatia
Žarko Babić orcid id orcid.org/0000-0002-5108-5433 ; Department of Gastroenterology, Hepatology and Clinical Nutrition, Dubrava University Hospital, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia; Division of Interventional Gastroenterology, Dubrava University Hospital, Zagreb, Croatia
Marko Banić ; Department of Gastroenterology, Hepatology and Clinical Nutrition, Dubrava University Hospital, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia; School of Medicine, University of Rijeka, Rijeka, Croatia; Division of Inflammatory Bowel Disease and Clinical Nutrition, Dubrava University Hospital, Zagreb, Croatia
Lana Ljubičić ; Zagreb Health Center-Center, Zagreb, Croatia


Puni tekst: engleski pdf 278 Kb

str. 731-738

preuzimanja: 346

citiraj


Sažetak

Dyspepsia is a disorder characterized by dyspeptic symptoms which are located in
the epigastrium and related to digestion of food in the initial part of the digestive system. In functional
dyspepsia, unlike organic dyspepsia, there is no underlying organic disease that would cause
dyspeptic symptoms. Immune and mucosal function changes, gastric dysmotility, different composition
of the gastrointestinal microbiota, and altered central nervous system processing are considered
responsible for the onset of the disorder. The diagnosis is based on history, clinical presentation, and
exclusion of other organic diseases of the gastrointestinal tract manifested by dyspeptic symptoms.
Therapy includes eradication of Helicobacter pylori infection, proton pump inhibitors, prokinetics, neuromodulators,
and herbal preparations. Unfortunately, in some patients, this therapy leads to little or
no improvement. The prevalence of functional dyspepsia is increasing. It has become one of the more
common gastroenterological diagnoses. In order to reduce the costs associated with the diagnosis and
treatment of the disorder itself, its mechanisms need to be fully elucidated and thus enable finding
appropriate therapy for all patient subgroups.

Ključne riječi

Dyspepsia; Helicobacter pylori; Hypersensitivity; Visceral pain; Microbiota

Hrčak ID:

275518

URI

https://hrcak.srce.hr/275518

Datum izdavanja:

1.12.2021.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.540 *