Medicina Fluminensis, Vol. 60 No. 3, 2024.
Pregledni rad
https://doi.org/10.21860/medflum2024_319215
Cardiovascular Risk Factors Among Patients with Severe Mental Disorders: An Overview and the Role of Cardio-Psychiatry in Prevention Strategies
Sergej Nadalin
; Opća bolnica „Dr. Josip Benčević“, Odjel za psihijatriju, Slavonski Brod, Hrvatska; Hrvatsko katoličko sveučilište, Medicinski fakultet, Zagreb, Hrvatska
*
Domagoj Vučić
; Opća bolnica „Dr. Josip Benčević“, Odjel za kardiologiju, Slavonski Brod, Hrvatska
Maja Vilibić
; Hrvatsko katoličko sveučilište, Medicinski fakultet, Zagreb, Hrvatska; Klinički bolnički centar Sestre milosrdnice, Klinika za psihijatriju, Zagreb, Hrvatska
Vjekoslav Peitl
; Hrvatsko katoličko sveučilište, Medicinski fakultet, Zagreb, Hrvatska; Klinički bolnički centar Sestre milosrdnice, Klinika za psihijatriju, Zagreb, Hrvatska
Luka Maršić
; Opća bolnica „Dr. Josip Benčević“, Centar za hitnu medicinu OHBP, Slavonski Brod, Hrvatska
Ivica Dunđer
; Opća bolnica „Dr. Josip Benčević“, Odjel za kardiologiju, Slavonski Brod, Hrvatska
Katica Cvitkušić Lukenda
; Opća bolnica „Dr. Josip Benčević“, Odjel za kardiologiju, Slavonski Brod, Hrvatska
Dalibor Karlović
; Hrvatsko katoličko sveučilište, Medicinski fakultet, Zagreb, Hrvatska; Klinički bolnički centar Sestre milosrdnice, Klinika za psihijatriju, Zagreb, Hrvatska
* Dopisni autor.
Sažetak
Individuals with severe mental disorders comprising schizophrenia, major depressive disorder and bipolar affective disorder have a life expectancy 15 – 25 years shorter compared to individuals from the general population. The high rate of unnatural deaths (predominantly, suicides) significantly contributes to reduced life expectancy among individuals with severe mental disorders. Like among individuals from the general population, cardiovascular diseases have been recognized as a main contributing factor to reduced life expectancy among individuals with severe mental disorders. Many cardiovascular risk factors among individuals with severe mental disorders, such as unhealthy dietary pattern, cigarette smoking and reduced physical activity are also present among individuals from the general population. Additional risk factor among individuals with severe mental disorders include the use of psychotropic medications, shared genetic vulnerability and intriguing interaction between cardiovascular risk factors. In the research literature, there is still a lack of studies on systematic assessment of cardiovascular risk factors among individuals with severe mental disorders, specifically on their interaction. In clinical practice, comorbidity of cardiovascular diseases and severe mental disorders is likely to be underrecognized and undertreated. In this article we discuss the risk factors for cardiovascular diseases among individuals with severe mental disorders, highlighting the role of multidisciplinary approach comprising psychiatry and cardiology teams in prevention strategies. Furthermore, we provide novel insights related to the genetic relationship between severe mental disorders and cardiovascular diseases, based on genome-wide association studies. Finally, we discuss clinically significant interactions between common cardiovascular and psychotropic medications and neuropsychiatric effects of common cardiovascular medications.
Ključne riječi
cardiovascular diseases; mental disorders; prevention and control; risk factors
Hrčak ID:
319215
URI
Datum izdavanja:
1.9.2024.
Posjeta: 383 *