Pregledni rad

https://doi.org/10.26800/LV-147-1-2-5

Extracorporeal CO2 removal in acute COPD exacerbation

TATJANA KEREŠ orcid.org/0000-0002-7254-4264 *
STJEPAN BUDIŠA

* Dopisni autor.

Sažetak

Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a frequent and serious clinical condition with acute deterioration of lung ventilatory function with resulting hypercapnia and hypoxemia, i.e. global respiratory insufficiency. In addition to pharmacological therapy with bronchodilators, antibiotics and corticosteroids, application of non-invasive positive pressure ventilation is the basis of treatment. However, 20–30% of critical patients are refractory to the applied non-invasive ventilation with progression of respiratory insufficiency, which requires invasive mechanical ventilation and the need for patient treatment in the intensive care unit. The modern method of extracorporeal CO2 removal from the blood (ECCO2R) is a new treatment modality for hypercapnia and respiratory acidosis using a device for extracorporeal blood circulation with CO2 exchange through a special membrane. Also, the mentioned modality finds its application in facilitated weaning from invasive mechanical ventilation. This paper will present the latest data on the application of ECCO2R in the treatment
of AECOPD.

Ključne riječi

PULMONARY DISEASE, CHRONIC OBSTRUCTIVE – complications, physiopathology, therapy; HYPERCAPNIA – etiology, therapy; ACIDOSIS, RESPIRATORY – etiology, therapy; CARBON DIOXIDE – blood; NONINVASIVE VENTILATION – methods; EXTRACORPOREAL MEMBRANE OXYGENATION – methods; EXTRACORPOREAL CIRCULATION; DISEASE PROGRESSION

Hrčak ID:

328793

URI

https://hrcak.srce.hr/328793

Datum izdavanja:

10.3.2025.

Podaci na drugim jezicima: hrvatski

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