Izvorni znanstveni članak

https://doi.org/10.21278/TOF.493068624

Study of Electrospun Fibrous Scaffolds for Vascular Grafts

Andžela Šešok orcid.org/0000-0001-8194-1539 ; Vilnius Gediminas Technical University, Department of Biomechanical Engineering, Vilnius, Lithuania *
Radvilė Jankauskytė ; Vilnius Gediminas Technical University, Department of Biomechanical Engineering, Vilnius, Lithuania
Dovydas Cicėnas ; Vilnius Gediminas Technical University, Department of Biomechanical Engineering, Vilnius, Lithuania
Rimantas Stonkus ; Vilnius Gediminas Technical University, Department of Mechatronics, Robotics and Digital Manufacturing, Vilnius, Lithuania
Jelena Škamat orcid.org/0000-0002-4441-6839 ; Vilnius Gediminas Technical University, Department of Mechanical and Materials Engineering, Vilnius, Lithuania

* Dopisni autor.

Sažetak

This paper focuses on the study of the mechanical, hydrophilic, and porous properties of vascular scaffolds obtained by electrospinning. Hybrid vascular scaffolds are made of a synthetic polymer, polycapralactone (PCL), and a natural polymer, type I collagen. The purpose of this work is to determine the effect of the collagen content and the concentration of PCL in solution on the mechanical properties of the vascular scaffolds. Using electrospinning technology, three different nanofibers were prepared with a base solution of PCL in chloroform solvent, at different concentrations (10%, 12% and 15%) and different amounts of collagen (2 ml, 3 ml and 5 ml). The resulting nanofibers were subjected to bench tensile tests and morphological structure analysis. The contact angle of the electrospun nanofibers was monitored. The porosity of the scaffolds was evaluated using the liquid penetration method. The results of the study show that the mechanical properties differ depending on the concentration of the solution and the amount of collagen in the solution.

Ključne riječi

electrospinning; blood vessels; scaffolds; polycapralactone; mechanical properties

Hrčak ID:

335584

URI

https://hrcak.srce.hr/335584

Datum izdavanja:

19.9.2025.

Posjeta: 1.043 *