Short communication, Note
Does Probiotic Yeast Act as Antigenotoxin?
Malda Maija Toma
; Institute of Microbiology and Biotechnology, University of Latvia, Kronvalda boulv. 4, LV-1586, Riga, Latvia
Jekabs Raipulis
; Institute of Microbiology and Biotechnology, University of Latvia, Kronvalda boulv. 4, LV-1586, Riga, Latvia
Inta Kalnina
; Institute of Microbiology and Biotechnology, University of Latvia, Kronvalda boulv. 4, LV-1586, Riga, Latvia
Reinis Rutkis
; Institute of Microbiology and Biotechnology, University of Latvia, Kronvalda boulv. 4, LV-1586, Riga, Latvia
Abstract
The effect of probiotic yeast Saccharomyces boulardii on genotoxicity induced by the well-known mutagen 4-nitroquinoline-N-oxide (4-NQO), as well as antibacterial (furazolidone) and antibiotic (nalidixic acid) drugs, has been studied using the short-term bacterial assay, SOS chromotest, with Escherichia coli PQ 37 as the test organism. It has been shown that S. boulardii possesses antigenotoxic activity, revealed by SOS chromotest, when coincubated with these genotoxins. A weaker antigenotoxic activity against the same compounds was observed with S. carlsbergensis, too.
Keywords
Saccharomyces boulardii; genotoxins; SOS chromotest; antigenotoxicity
Hrčak ID:
110555
URI
Publication date:
15.9.2005.
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