Review article
https://doi.org/10.15255/KUI.2022.042
Ecotoxicity of Non-steroidal Anti-inflammatory Drugs on Aquatic Organisms
Danijela Bićanić
orcid.org/0009-0002-2076-0464
; University of Zagreb, Faculty of Chemical Engineering and Technology, Trg Marka Marulića 19, 10 000 Zagreb, Croatia
Antonela Čugalj
orcid.org/0009-0005-2363-5679
; University of Zagreb, Faculty of Chemical Engineering and Technology, Trg Marka Marulića 19, 10 000 Zagreb, Croatia
Marko Jajčević
orcid.org/0009-0001-8809-0762
; University of Zagreb, Faculty of Chemical Engineering and Technology, Trg Marka Marulića 19, 10 000 Zagreb, Croatia
Antonija Lazinica
; University of Zagreb, Faculty of Chemical Engineering and Technology, Trg Marka Marulića 19, 10 000 Zagreb, Croatia
Martina Miloloža
orcid.org/0000-0003-3719-8359
; University of Zagreb, Faculty of Chemical Engineering and Technology, Trg Marka Marulića 19, 10 000 Zagreb, Croatia
Dajana Kučić Grgić
; University of Zagreb, Faculty of Chemical Engineering and Technology, Trg Marka Marulića 19, 10 000 Zagreb, Croatia
Abstract
In today’s modern world, it is difficult to imagine life without the use of non-steroidal anti-inflammatory drugs. Namely, due to easy availability, we witness their increasing presence in all components of the environment, where they most often end up due to improper disposal or via wastewater. Therefore, it is important to note that non-steroidal anti-inflammatory drugs can often be found as part of wastewater originating from pharmaceutical industries and hospitals, as well as municipal wastewater. In the last few decades, scientists have become aware that these drugs represent a great danger because, in addition to polluting all components of the environment, they also cause negative consequences for organisms present in the environment, thus, more time is being devoted to conducting ecotoxicity tests. Ecotoxicity tests are the best solution for monitoring the negative effects of individual substances and/or their mixtures on the organisms, whereby a negative effect for humans can be predicted as well.
This paper provides an overview of previous research related to non-steroidal anti-inflammatory drugs and their role in the food chain. An overview of several types of drugs such as ibuprofen, diclofenac, and ketoprofen is given, as well as their effect on certain organisms such as Daphnia magna, Danio rerio, Tinca tinca, and Navicula sp.
Keywords
non-steroidal anti-inflammatory drugs; ibuprofen; diclofenac; ketoprofen; ecotoxicity tests
Hrčak ID:
295655
URI
Publication date:
14.3.2023.
Visits: 663 *