Ostalo
https://doi.org/10.26332/y03ve736
The Relationship of C-Reactive Protein to Albumin Ratio with Three-Month Survival in Hospitalized Patients with Heart Failure
Željka Dragila
orcid.org/0000-0001-9500-0625
; Department of Emergency Medicine, University Hospital Centre Osijek, Croatia; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia
*
Lea Maršić
; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Department of Emergency Medicine, General Hospital Našice, Croatia
Anamaria Mikolčić
; Department of Emergency Medicine, University Hospital Centre Osijek, Croatia
Romana Marušić
; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Department of Internal Medicine, National Memory Hospital Vukovar, Croatia
Lana Maričić
orcid.org/0000-0001-6035-6760
; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Department of Cardiology, Department of Internal Medicine, University Hospital Centre Osijek, Croatia
* Dopisni autor.
Sažetak
Aim of the study: This study aimed to investigate the association of the C-reactive protein (CRP) to albumin ratio with three-month survival after hospitalization for heart failure. Methods: Patients hospitalized for heart failure at Department of Cardiology, University Hospital Centre Osijek in the period of 10 months were included. Results: There were 145 patients, of whom 67 (46.2%) were male and 78 (53.8%) female. The median age was 74 years (interquartile range 65–82 years). The most common comorbidities were hypertension (83.4%) and atrial fibrillation (58.6%). Patients treated with mineralocorticoid receptor antagonist (P = 0.02) and furosemide (P = 0.04) had a significantly higher CRP/albumin ratio. A significant positive correlation of CRP/albumin ratio was observed with neutrophil percentage, red cell distribution width, N-terminal pro-B-type natriuretic peptide, and urate concentration, whereas a significant negative correlation of CRP/albumin ratio was observed with diastolic arterial pressure, lymphocyte percentage, haemoglobin, prothrombin time and sodium concentration. Elevated CRP/albumin ratio was associated with higher mortality during the three-month follow-up (P = 0.04). Additionally, higher mortality was observed in patients with chronic obstructive pulmonary disease, a mineralocorticoid receptor antagonist and furosemide in therapy, lower systolic and diastolic blood pressure as well as higher urea, creatinine and urate concentration.Conclusion: The CRP/albumin ratio shows a greater association with the three-month survival of hospitalized patients for heart failure than CRP and albumin individually.
Ključne riječi
albumin; C-reactive protein; heart failure; survival
Hrčak ID:
345715
URI
Datum izdavanja:
23.3.2026.
Posjeta: 204 *