Izvorni znanstveni članak
https://doi.org/10.31306/s.68.1.2
Antineoplastic drugs in hospital administration units: Use of automatic toilet seats to contain surface contaminations in washrooms
Stefano Dugheri
orcid.org/0009-0001-2412-5882
; Link Campus University, Rome, Italy
*
Donato Squillaci
; University of Florence, Florence, Italy
Ilaria Rapi
; University of Florence, Florence, Italy
Giovanni Cappelli
; University of Florence, Florence, Italy
Antonio Marigliano
; University of Florence, Florence, Italy
Fabrizio Dori
; Careggi University Hospital, Health and Safety Service, Florence, Italy
Giorgio Marrubini
; University of Pavia, Department of Drug Sciences, Pavia, Italy
Niccolò Fanfani
; University of Florence, Department of Experimental and Clinical Medicine, Florence, Italy
Antonio Baldassarre
; University of Florence, Florence, Italy
Simone De Sio
; University of Rome “Sapienza”, Rome, Italy
Nicola Mucci
; University of Florence, Florence, Italy
Veronica Traversini
; University of Florence, Florence, Italy
* Dopisni autor.
Sažetak
The contamination of surfaces by antineoplastic drugs represents an increasing risk factor within healthcare environments. The primary causes are the rise in the number of prescriptions and patients treated in hospital oncology departments. Protective measures are implemented to safeguard workers involved in drug preparation within compounding units and administration units. The focus is on preventing contamination at the level of transfusion bags, while contamination from the biological fluids of treated patients, particularly urine, is significantly underestimated. Incorrect use of the toilet by patients due to ongoing intravenous therapy and poor personal hygiene is, at the time being, the most notable source of contamination inside administration units. In this context, the use of automatic toilet seats was tested in the departments of an Italian hospital to reduce the risk associated with the administration of antineoplastic drugs while simultaneously increasing the comfort of patients during day hospital treatments. The primary objective was to achieve a measurable reduction in surface contamination levels and thus assess improvements in patient and staff safety. Contamination levels of various surfaces inside the washrooms were monitored using UV lamps, focusing on the washroom floor, the surface of the toilet seat, and faucet. Samples were collected through wipe test sampling and then analysed using a UHPLC-MS/MS system. The results from the analyses and evaluations showed a promising reduction in contamination of the selected areas thanks to the use of the tested devices, accompanied by strong positive feedback from users.
Ključne riječi
antineoplastic drugs, occupational exposure, automatic toilet seat, wipe test, surface contamination
Hrčak ID:
346588
URI
Datum izdavanja:
27.4.2026.
Posjeta: 70 *