Acta clinica Croatica, Vol. 65. No. 2, 2026.
Izvorni znanstveni članak
https://doi.org/10.20471/acc.2026.65.02.11
Minor Airway Interventions in Elderly Patients Undergoing ERCP With High Flow Versus Conventional Nasal Cannula Oxygen Therapy: A Randomized Controlled Trial
Valentina Ješić
orcid.org/0000-0001-7947-5233
; Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; Faculty of Health Sciences, University of Novo mesto, Novo mesto, Slovenia
*
Tihana Magdić Turković
orcid.org/0000-0003-1193-512X
; Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Marinko Vučić
; Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
* Dopisni autor.
Sažetak
Intravenous sedation for endoscopic retrograde cholangiopancreatography
(ERCP) in patients aged 65 years or older is associated with respiratory instability.
During ERCP, oxygen therapy is commonly delivered using a conventional
nasal cannula (CNC) or a high flow nasal cannula (HFNC). Respiratory instability
may require minor airway interventions (MAI), including chin lift, secretion suctioning,
the insertion of an oropharyngeal airway, or escalation from CNC to
HFNC. This randomized controlled trial aimed to compare the incidence of MAI
in patients receiving HFNC versus CNC during ERCP.
In this single center, prospective, randomized, controlled trial, 115 patients aged
65 years or older undergoing ERCP under intravenous sedation were randomized
to HFNC (n = 58) or CNC (n = 57). The primary outcome was the incidence
of MAI in each group.
MAI occurred in 30 patients (26.1%) overall and significantly less frequently
in the HFNC group (7 of 58, 12.1%) than in the CNC group (23 of 57, 40.4%)
(P < 0.001; relative risk (RR) 0.30, 95% confidence interval (CI) 0.14–0.64). Chin
lift was the most frequent MAI. No associations between MAI and age, sex, or
the American Society of Anesthesiologists (ASA) physical status were observed.
HFNC significantly reduces the incidence of MAI compared with conventional
nasal cannula oxygen therapy.
Ključne riječi
Aged; Airway management; Conscious sedation; Endoscopic retrograde cholangiopancreatography; High flow nasal cannula; Oxygen inhalation therapy
Hrčak ID:
347696
URI
Datum izdavanja:
10.6.2026.
Posjeta: 0 *