Pregledni rad
https://doi.org/10.15255/KUI.2014.020
1,3-Dipolar Cycloaddition (Part I): Synthesis of 1,2,3-Triazole Derivatives in Nucleoside Chemistry
D. Saftić
; Zavod za organsku kemiju i biokemiju, Institut Ruđer Bošković, Bijenička cesta 54, 10 000 Zagreb, Hrvatska
L. Krstulović
; Zavod za kemiju i biokemiju, Veterinarski fakultet, Sveučilište u Zagrebu Heinzelova 55, 10 000 Zagreb, Hrvatska
M. Bajić
; Zavod za kemiju i biokemiju, Veterinarski fakultet, Sveučilište u Zagrebu Heinzelova 55, 10 000 Zagreb, Hrvatska
B. Žinić
; Zavod za organsku kemiju i biokemiju, Institut Ruđer Bošković, Bijenička cesta 54, 10 000 Zagreb, Hrvatska
Sažetak
Copper catalysed Huisgen 1,3-dipolar cycloaddition of azides and alkynes which leads to 1,4-disubstituted-1,2,3-triazoles is a frequently used method in synthetic organic chemistry. Due to the simple reaction conditions, it has occupied an important place in the field of nucleoside chemistry since it enables preparation of a large number of potentially biologically active compounds with a number of interesting additional properties induced by the presence of 1,2,3-triazole structural motif in the molecule.
Ključne riječi
Click chemistry; nucleosides; 1,2,3-triazole nucleoside analogs
Hrčak ID:
145123
URI
Datum izdavanja:
17.9.2015.
Posjeta: 1.807 *