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Food Technology and Biotechnology, Vol.56 No.2 Lipanj 2018.

Prethodno priopćenje
https://doi.org/10.17113/ftb.56.02.18.5474

Učinak ekstrakata kratkozupčaste i dalmatinske kadulje na agregaciju trombocita

Andrea Antolić ; University of Zagreb, Faculty of Science, Roosevelt Square 6, HR- 10000 Zagreb, Croatia
Željan Maleš ; University of Zagreb, Faculty of Pharmacy and Biochemistry, Department of Pharmaceutical Botany, Schrottova 39, HR-10000 Zagreb, Croatia
Maja Tomičić ; Croatian Institute of Transfusion Medicine, Department of Platelet and Leukocyte Immunology, Petrova 6, HR-10000 Zagreb, Croatia
Mirza Bojić ; University of Zagreb, Faculty of Pharmacy and Biochemistry, Department of Medicinal Chemistry, A. Kovačića 1, HR-10000 Zagreb, Croatia

Puni tekst: hrvatski, pdf (164 KB) str. 265-269 preuzimanja: 14* citiraj
APA 6th Edition
Antolić, A., Maleš, Ž., Tomičić, M. i Bojić, M. (2018). Učinak ekstrakata kratkozupčaste i dalmatinske kadulje na agregaciju trombocita. Food Technology and Biotechnology, 56 (2), 265-269. https://doi.org/10.17113/ftb.56.02.18.5474
MLA 8th Edition
Antolić, Andrea, et al. "Učinak ekstrakata kratkozupčaste i dalmatinske kadulje na agregaciju trombocita." Food Technology and Biotechnology, vol. 56, br. 2, 2018, str. 265-269. https://doi.org/10.17113/ftb.56.02.18.5474. Citirano 21.11.2018.
Chicago 17th Edition
Antolić, Andrea, Željan Maleš, Maja Tomičić i Mirza Bojić. "Učinak ekstrakata kratkozupčaste i dalmatinske kadulje na agregaciju trombocita." Food Technology and Biotechnology 56, br. 2 (2018): 265-269. https://doi.org/10.17113/ftb.56.02.18.5474
Harvard
Antolić, A., et al. (2018). 'Učinak ekstrakata kratkozupčaste i dalmatinske kadulje na agregaciju trombocita', Food Technology and Biotechnology, 56(2), str. 265-269. doi: https://doi.org/10.17113/ftb.56.02.18.5474
Vancouver
Antolić A, Maleš Ž, Tomičić M, Bojić M. Učinak ekstrakata kratkozupčaste i dalmatinske kadulje na agregaciju trombocita. Food Technology and Biotechnology [Internet]. 2018 [pristupljeno 21.11.2018.];56(2):265-269. doi: https://doi.org/10.17113/ftb.56.02.18.5474
IEEE
A. Antolić, Ž. Maleš, M. Tomičić i M. Bojić, "Učinak ekstrakata kratkozupčaste i dalmatinske kadulje na agregaciju trombocita", Food Technology and Biotechnology, vol.56, br. 2, str. 265-269, 2018. [Online]. doi: https://doi.org/10.17113/ftb.56.02.18.5474
Puni tekst: engleski, pdf (164 KB) str. 265-269 preuzimanja: 23* citiraj
APA 6th Edition
Antolić, A., Maleš, Ž., Tomičić, M. i Bojić, M. (2018). The Effect of Short-Toothed and Dalmatian Sage Extracts on Platelet Aggregation. Food Technology and Biotechnology, 56 (2), 265-269. https://doi.org/10.17113/ftb.56.02.18.5474
MLA 8th Edition
Antolić, Andrea, et al. "The Effect of Short-Toothed and Dalmatian Sage Extracts on Platelet Aggregation." Food Technology and Biotechnology, vol. 56, br. 2, 2018, str. 265-269. https://doi.org/10.17113/ftb.56.02.18.5474. Citirano 21.11.2018.
Chicago 17th Edition
Antolić, Andrea, Željan Maleš, Maja Tomičić i Mirza Bojić. "The Effect of Short-Toothed and Dalmatian Sage Extracts on Platelet Aggregation." Food Technology and Biotechnology 56, br. 2 (2018): 265-269. https://doi.org/10.17113/ftb.56.02.18.5474
Harvard
Antolić, A., et al. (2018). 'The Effect of Short-Toothed and Dalmatian Sage Extracts on Platelet Aggregation', Food Technology and Biotechnology, 56(2), str. 265-269. doi: https://doi.org/10.17113/ftb.56.02.18.5474
Vancouver
Antolić A, Maleš Ž, Tomičić M, Bojić M. The Effect of Short-Toothed and Dalmatian Sage Extracts on Platelet Aggregation. Food Technology and Biotechnology [Internet]. 2018 [pristupljeno 21.11.2018.];56(2):265-269. doi: https://doi.org/10.17113/ftb.56.02.18.5474
IEEE
A. Antolić, Ž. Maleš, M. Tomičić i M. Bojić, "The Effect of Short-Toothed and Dalmatian Sage Extracts on Platelet Aggregation", Food Technology and Biotechnology, vol.56, br. 2, str. 265-269, 2018. [Online]. doi: https://doi.org/10.17113/ftb.56.02.18.5474

Rad u XML formatu

Sažetak
Kadulja (Salvia sp.) je rod mediteranskih biljaka koji se koristi za aromatiziranje hrane. U ovom su radu ispitani ukupni udjel polifenola, antioksidacijska svojstva i antitrombocitni učinak kratkozupčaste kadulje (Salvia brachyodon Vandas), te su uspoređeni s najčešće korištenom vrstom kadulje (S. officinalis, tj. dalmatinska kadulja). Udjel ukupnih flavonoida iznosio je 0,08-0,23 %, a fenolnih kiselina 0,47-3,04 %. Antioksidacijska aktivnost kratkozupčaste kadulje, ispitana pomoću DPPH testa, bila je izraženija (29-36 mg/mL ekvivalenata galne kiseline) od aktivnosti dalmatinske kadulje. U funkcionalnom testu primarne hemostaze, ekstrakt kratkozupčaste kadulje nanomolarne koncentracije od 21 nM spriječio je agregaciju trombocita, čime je potvrđeno da se može upotrijebiti za prevenciju tromboze, i to kao funkcionalna hrana ili nadomjestak prehrani. Antitrombocitna aktivnost povezana je s antioksidacijskim kapacitetom (r=0,7014, p=0,0352), što upućuje na zaključak da na prevenciju agregacije ne utječe samo jedan spoj, već je to rezultat sinergističkog učinka polifenola. Dobiveni rezultati su preliminarni i zahtijevaju detaljnije ispitivanje moguće primjene navedenih biljnih vrsta u svrhu prevencije kardiovaskularnih bolesti i agregacije trombocita.

Ključne riječi
kadulja; flavonoidi; fenolne kiseline; agregacija trombocita

Hrčak ID: 203495

URI
https://hrcak.srce.hr/203495

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[engleski]

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