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RATIONAL USE OF ANTIMICROBIAL DRUGS IN CLINICAL PRACTICE BY IMPLEMENTING ANTIMICROBIAL STEWARDSHIP PROGRAMS
SANJA SAKAN
orcid.org/0000-0002-9551-413X
; Klinika za kardiovaskularne bolesti Magdalena, Krapinske Toplice, Hrvatska
DAVORKA PRAJDIĆ-PREDRIJEVAC
; Klinika za kardiovaskularne bolesti Magdalena, Krapinske Toplice, Hrvatska
VLADO JURANKO
; Klinika za kardiovaskularne bolesti Magdalena, Krapinske Toplice, Hrvatska
MLADEN NOVKOSKI
; Klinika za kardiovaskularne bolesti Magdalena, Krapinske Toplice, Hrvatska
ZDENKO POVŠIĆ-ČEVRA
; Klinika za kardiovaskularne bolesti Magdalena, Krapinske Toplice, Hrvatska
JANKO SZAVITS-NOSSAN
; Klinika za kardiovaskularne bolesti Magdalena, Krapinske Toplice, Hrvatska
IGOR ŠESTO
; Klinika za kardiovaskularne bolesti Magdalena, Krapinske Toplice, Hrvatska
MARIJA RAZUM
; Klinika za kardiovaskularne bolesti Magdalena, Krapinske Toplice, Hrvatska
LUKA ROTKVIĆ
; Klinika za kardiovaskularne bolesti Magdalena, Krapinske Toplice, Hrvatska
IVAN BUDIMIR
orcid.org/0000-0002-0202-9208
; Klinika za kardiovaskularne bolesti Magdalena, Krapinske Toplice, Hrvatska
NIVES TODORIĆ
; Klinika za kardiovaskularne bolesti Magdalena, Krapinske Toplice, Hrvatska
NATAŠA ANDRIJAŠEVIĆ
; Klinička bolnica Sveti Duh, Zavod za kliničku mikrobiologiju i hospitalne infekcije, Zagreb, Hrvatska
ZVONIMIR ANTE KORDA
; Klinika za kardiovaskularne bolesti Magdalena, Krapinske Toplice, Hrvatska
Sažetak
According to studies, about 50% of antimicrobial drugs are prescribed unnecessarily and inappropriately in hospitals and other healthcare institutions. Besides the high prevalence of Clostridium diffi cile infection, of particular concern is the increase in bacterial pathogen resistance to fl uoroquinolones and vancomycin-resistant enterococci. Additionally, infections due to bacterial pathogens completely resistant to carbapenems are currently emerging in Europe. In this case, therapeutic options are limited to the use of the polymyxin antibiotic colistin, which is old and has many adverse and toxic events. Growing evidence demonstrates that hospital programs dedicated to improving the use of antimicrobial therapy, referred to as Antimicrobial Stewardship Programs (ASP), can optimize treatment of infections, reduce adverse events of antimicrobial therapy, improve patient safety and quality of care, and at the same time signifi cantly reduce hospital costs, mortality rate and length of hospital stay. Therefore, the US Centers for Disease Control and Prevention and European Centre for Disease Prevention and Control recommend that every acute care hospital implement the multidisciplinary ASP in daily clinical practice.
Ključne riječi
antibiotic; hospital; infection; resistance
Hrčak ID:
208537
URI
Datum izdavanja:
16.11.2018.
Posjeta: 1.641 *