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Antioxidant, α-glucosidase and 15-lipoxygenases inhibitory activities of Cassia singueana Del. and C. sieberiana DC. (Fabaceae)

Saidu Jibril   ORCID icon orcid.org/ORCID ; Department of Chemical Sciences, Faculty of Science, Federal University of Kashere, P. M. B. 0182, Gombe, Nigeria
Wan Mohd Nuzul Hakimi Wan Salleh   ORCID icon orcid.org/ORCID ; Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjung Malim, Perak, Malaysia
Hasnah Mohd Sirat   ORCID icon orcid.org/ORCID ; Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, 81310 Skudai, Johor, Malaysia
Dalha Wada Taura   ORCID icon orcid.org/ORCID ; Department of Microbiology, Faculty of Life Science, College of Pharmaceutical and Life Sciences, Bayero University Kano, P.M.B. 3011, Kano Nigeria
Yusha’u Muhammad   ORCID icon orcid.org/ORCID ; Department of Microbiology, Faculty of Life Science, College of Pharmaceutical and Life Sciences, Bayero University Kano, P.M.B. 3011, Kano Nigeria
Abdu Zakari   ORCID icon orcid.org/ORCID ; Department of Chemical Sciences, Faculty of Science, Federal University of Kashere, P. M. B. 0182, Gombe, Nigeria

Puni tekst: engleski, pdf (541 KB) str. 345-351 preuzimanja: 71* citiraj
APA 6th Edition
Jibril, S., Salleh, W.M.N.H.W., Sirat, H.M., Taura, D.W., Muhammad, Y. i Zakari, A. (2020). Antioxidant, α-glucosidase and 15-lipoxygenases inhibitory activities of Cassia singueana Del. and C. sieberiana DC. (Fabaceae). Agriculturae Conspectus Scientificus, 85 (4), 345-351. Preuzeto s https://hrcak.srce.hr/245973
MLA 8th Edition
Jibril, Saidu, et al. "Antioxidant, α-glucosidase and 15-lipoxygenases inhibitory activities of Cassia singueana Del. and C. sieberiana DC. (Fabaceae)." Agriculturae Conspectus Scientificus, vol. 85, br. 4, 2020, str. 345-351. https://hrcak.srce.hr/245973. Citirano 28.10.2021.
Chicago 17th Edition
Jibril, Saidu, Wan Mohd Nuzul Hakimi Wan Salleh, Hasnah Mohd Sirat, Dalha Wada Taura, Yusha’u Muhammad i Abdu Zakari. "Antioxidant, α-glucosidase and 15-lipoxygenases inhibitory activities of Cassia singueana Del. and C. sieberiana DC. (Fabaceae)." Agriculturae Conspectus Scientificus 85, br. 4 (2020): 345-351. https://hrcak.srce.hr/245973
Harvard
Jibril, S., et al. (2020). 'Antioxidant, α-glucosidase and 15-lipoxygenases inhibitory activities of Cassia singueana Del. and C. sieberiana DC. (Fabaceae)', Agriculturae Conspectus Scientificus, 85(4), str. 345-351. Preuzeto s: https://hrcak.srce.hr/245973 (Datum pristupa: 28.10.2021.)
Vancouver
Jibril S, Salleh WMNHW, Sirat HM, Taura DW, Muhammad Y, Zakari A. Antioxidant, α-glucosidase and 15-lipoxygenases inhibitory activities of Cassia singueana Del. and C. sieberiana DC. (Fabaceae). Agriculturae Conspectus Scientificus [Internet]. 2020 [pristupljeno 28.10.2021.];85(4):345-351. Dostupno na: https://hrcak.srce.hr/245973
IEEE
S. Jibril, W.M.N.H.W. Salleh, H.M. Sirat, D.W. Taura, Y. Muhammad i A. Zakari, "Antioxidant, α-glucosidase and 15-lipoxygenases inhibitory activities of Cassia singueana Del. and C. sieberiana DC. (Fabaceae)", Agriculturae Conspectus Scientificus, vol.85, br. 4, str. 345-351, 2020. [Online]. Dostupno na: https://hrcak.srce.hr/245973. [Citirano: 28.10.2021.]

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Sažetak
The present study investigates the antioxidant, α-glucosidases, and anti-inflammatory properties of leaf extract of Cassia singueana and C. sieberiana. Cassia singueana and C. sieberiana are restorative plants utilised for the treatment of diabetes, ulcer, malaria, and wound healing. The extracts were evaluated for antioxidant activities via DPPH radical scavenging, ABTS+ radical cation scavenging, FRAP, β-carotene bleaching, phenolic content, and flavonoid content. Meanwhile, α-glucosidases and anti-inflammatory properties were also evaluated against α-glucosidase enzyme and 15-LOX inhibitory activities. The results for C. singueana extract revealed potent activities for DPPH (IC50: 9.35 µg/mL), phenolic contents (120.01 mg GAE/g dry extract), and α-glucosidases inhibition (I%: 90.47%). On the other hand, the findings for C. sieberiana recorded significant activities for FRAP (2120 µmol Fe2+/g dry extract) and 15-LOX inhibition (I%: 80.93%). The extract of C. singueana and C. sieberiana contain possible antioxidant, α-glucosidases, and anti-inflammatory agents that are responsible for the popular use of these plants in the treatment of diabetes and ulcer.

Ključne riječi
Cassia singueana, Cassia sieberiana, antioxidant, anti-inflammatory, anti-diabetic, Fabaceae

Hrčak ID: 245973

URI
https://hrcak.srce.hr/245973

Posjeta: 168 *