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https://doi.org/10.20471/acc.2025.64.04.11

Audiological Profile of OSA Patients: The Effect of Chronic Nocturnal Intermittent Hypoxia on Auditory Function; A Pilot Study

Mirjana Grebenar Čerkez orcid.org/0000-0002-3809-0529 ; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center Osijek, Osijek, Croatia *
Željko Zubčić ; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center Osijek, Osijek, Croatia
Stjepan Jurić ; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Department of Neurology, University Hospital Center Osijek, Osijek, Croatia
Jelena Šarić Jurić ; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Department of Neurology, University Hospital Center Osijek, Osijek, Croatia
Darija Birtić orcid.org/0000-0003-1661-7147 ; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center Osijek, Osijek, Croatia

* Dopisni autor.

Sažetak

Objective: The objective of this study was to investigate whether there is any positive
or negative correlation between inner ear function and obstructive sleep apnea (OSA).
Methods: The study included 35 patients diagnosed with moderate or severe OSA and a control
group consisting of 25 healthy individuals. Pure-tone audiometry, tympanometry, transient evoked
otoacoustic emissions (TEOAE), distortion product otoacoustic emissions (DPOAE) and auditory
brainstem response (ABR) tests were performed, evaluated and compared between the two groups.
Results: The air-conduction thresholds at 1000, 4000 and 8000 Hz were higher in OSA patients
compared to the controls (P < 0.05). Biauricular wave I and wave V latencies in the OSA group were
longer than in the control group, but were still within reference values (1.60 ± 0.45 vs 1.43 ± 0.16 ms,
P < 0.001; 5.52 ± 0.70 vs 5.47 ± 0.19 ms, P < 0.001). There was a significant difference in the wave I–V
interval between the two groups (4.17 ± 0.36 vs 4.03 ± 4.03 ± 0.16 ms, P < 0.006). An analysis of TEOAE
signal-to-noise ratio (SNR) mean values revealed a significant difference between the target OSA group
and the control group at 1.00 kHz, 1.42 kHz, 2.00 kHz, 2.83 kHz and 4.00 kHz (P < 0.001). An analysis
of DPOAE SNR mean values revealed a significant difference between OSA patients and the control
group at all tested frequencies (P < 0.027 for 500 Hz; P < 0.001 for 1000 to 8000 Hz).
Conclusion: There is a positive correlation between inner ear function and OSA. High-frequency
hearing loss was detected in adults with OSA. The results of otoacoustic emissions showed damage of
the cochlear receptor cells.

Ključne riječi

OSA; Inner ear; Pure-tone audiometry; DPOAE; TEOAE

Hrčak ID:

344723

URI

https://hrcak.srce.hr/344723

Datum izdavanja:

31.12.2025.

Podaci na drugim jezicima: hrvatski

Posjeta: 257 *