Pregledni rad

Biological activity of coumarin derivatives – a review

Maja Molnar ; Sveučilište Josipa Jurja Strossmayera u Osijeku, Prehrambeno-tehnološki fakultet Osijek, Franje Kuhača 20, 31000 Osijek, Hrvatska
M. Čačić ; Sveučilište Josipa Jurja Strossmayera u Osijeku, Prehrambeno-tehnološki fakultet Osijek, Franje Kuhača 20, 31000 Osijek, Hrvatska

Sažetak

Coumarin derivatives are wide spread in nature and found in many plants, fruits and vegetables. They show a broad spectrum of biological activities, but the use of coumarin is restricted by law and its maximal allowed concentration in foodstuff is determined by state regulations. As a model for investigation of coumarin toxicity rats have often been used, but some recent investigations indicate that the coumarin metabolism and therefore coumarin toxicity, are much different in humans and rats. This paper sums up coumarin biological properties as well as specificity of coumarin metabolism in rats and humans.

Ključne riječi

coumarin; metabolism; biological activity; toxicity

Hrčak ID:

76162

URI

https://hrcak.srce.hr/76162

Datum izdavanja:

30.12.2011.

Podaci na drugim jezicima: hrvatski

Posjeta: 7.503 *