Pregledni rad

https://doi.org/10.31895/hcptbn.17.1-2.7

Plant protein hydrolysates as animal cell culture media supplement

Višnja Gaurina Srček ; Prehrambeno-biotehnološki fakultet, Sveučilište u Zagrebu, Zagreb, Hrvatska
Tino Ursić ; Prehrambeno-biotehnološki fakultet, Sveučilište u Zagrebu, Zagreb, Hrvatska
Marijan Logarušić ; Prehrambeno-biotehnološki fakultet, Sveučilište u Zagrebu, Zagreb, Hrvatska
Kristina Radošević ; Prehrambeno-biotehnološki fakultet, Sveučilište u Zagrebu, Zagreb, Hrvatska
Igor Slivac orcid.org/0000-0002-8344-1244 ; Prehrambeno-biotehnološki fakultet, Sveučilište u Zagrebu, Zagreb, Hrvatska

Sažetak

Culture media containing essential nutrients like glucose, amino-acids and salts, as well as hormones, growth factors added by animal blood serum is required for bioprocesses with animal cells. Due to the disadvantages of serum use (e.g. risk of virus transmission, variation in composition, complex product isolation), the development of serum-free media supplemented with plant protein hydrolysates took place about two decades ago. The hydrolysates contain amino acids, oligopeptides, lipids, vitamins and other compounds that promote cell culture proliferation and productivity. This paper gives a brief overview of the preparation and the most important biological properties of protein hydrolysates with emphasis on the use of plant hydrolysates as components of animal cell culture media in the production of biopharmaceuticals.

Ključne riječi

biopharmaceuticals, biopeptides, protein hydrolysates, productivity

Hrčak ID:

287129

URI

https://hrcak.srce.hr/287129

Datum izdavanja:

14.12.2022.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.047 *